Team 1 - Liver Cancer and Tumor Invasion

Team 1 results from the gathering of scientists with the aim of performing both fundamental and translational research in the field of liver carcinogenesis.

Team leaders

Violaine MOREAU, DR2 INSERM
violaine.moreau@inserm.fr
+33 (0)5 57 57 12 72

Frédéric SALTEL, DR2 INSERM
frederic.saltel@inserm.fr
+33 (0)5 57 57 17 07

Research description

Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. It is the 6th most frequent cancer worldwide and the 2nd leading cause of cancer-related death. The overall poor prognosis of HCC is due to high rates of postoperative recurrence and metastasis incidence. Intrahepatic metastases, including satellite nodules and venous metastases, are hallmark features of HCC progression.

Cellular migration and invasion through tissue barriers is key in the dissemination of cancer cells during metastasis.
The aim of our research is to unravel the mechanisms that are implicated in tumor cell migration and invasion.

Our main research axes:

  • Mediators of liver carcinogenesis (beta-catenin, RhoGTPases, translation factors)
  • Molecular bases of tumor invasion (Invadosomes, Type I Collagen, discoidin domain receptors, RhoGTPases)
  • Translational research on liver tumors

Publications

Our Covers

Cover JBC Fred
Cover CAM
Cover MBoC2012
Cover BBA

Team members

member

status

affiliation

ALLAIN-COURTOIS Nathalie

Technician

University of Bordeaux

BALABAUD Charles

Pr Emeritus

University of Bordeaux

BASBOUS Sara

Post-doc

INSERM (CDD Fondation ARC)

BILLOTTET Clotilde

Assistant Professor

University of Bordeaux

BIOULAC-SAGE Paulette

Pr Emeritus

University of Bordeaux

BLANC Jean-Frédéric

PU-PH

University Hospital of Bordeaux

BOUCHECAREILH Marion

CRCN CNRS

CNRS

DE LEDINGHEN Victor

PU-PH

University Hospital of Bordeaux

DI TOMMASO Sylvaine

Engineer (CDD)

Ast Innovations

HENRIET Elodie

PhD student

University of Bordeaux

HERAUD Capucine

PhD student

University of Bordeaux

JABOUILLE Arnaud

Post-doc

INSERM (CDD Fondation de France)

LAGRÉE-BRINGTOWN Valérie

Assistant Professor

University of Bordeaux

LE BAIL Brigitte

PU-PH

University Hospital of Bordeaux

LEON Céline

Engineer

University of Bordeaux

MOREAU Mélanie

PhD student

University of Bordeaux

MOREAU Violaine

DR2 INSERM

INSERM

NEAUD Véronique

Technician

University of Bordeaux

PINAULT Mathilde

PhD student

University of Bordeaux

RAYMOND Anne-Aurélie

Post-doc

University Hospital of Bordeaux

ROS Manon

PhD student

University of Bordeaux

SALA Margaux

PhD student

University of Bordeaux

SALTEL Frédéric

DR2 INSERM

INSERM

 

Support

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Updated on 18/03/2020

FRM Team

Team 1 awarded FRM label in 2018 for three years