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microdissection and mass spectrometry method for proteomic analysis of Formalin-fixed, Paraffin-embedded (FFPE) tissue sections. Mass spectrometry is the method of choice to identify, characterize and quantify ... A combined laser microdissection and mass spectrometry method for proteomic analysis
invasion, liver cancer, actin cytoskeleton, invadosomes, small GTPases, metastases, Rho GTPases, collagen, DDR, proteomics
Combining laser capture micro-dissection and proteomics reveals an active translation machinery controlling invadosome formation
Zakaria Ezzoukhry#, Elodie Henriet#, Fabrice P. Cordelières, Jean
such as flow cytometry, lentiviral production… Members of the team are also developing an innovative proteomic facility called Oncoprot.
Each week an interactive team seminar is given in alternance
. Recently, in my group we developed a new methodology to define the proteome of low biological material obtained from subcellular compartment and adapted it to human tissues (hepatocellular carcinoma).
these goals, we use several approaches (exome sequencing, genetic screens and proteomic) and work in closed collaboration with clinical group (Pr Lachaux Team, Children’s Hospital, Lyon), academic team (Gliter