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Team 2 - Helicobacter infection: Inflammation and Cancer (27 January 2022)

. Our main research axes: Gastric MALT lymphoma and in particular on inflammatory and molecular responses in animal model of gastric MALT lymphoma development (Philippe Lehours) Cancer stem cells ... Team 2 research is dedicated to the study of the pathogenicity of Helicobacter, in particular in the context of digestive cancers associated to Helicobacter infection: Helicobacter pylori infection ... Team 2 - Helicobacter infection: Inflammation and Cancer

Group 2- Helicobacter pylori infection and gastric carcinoma (PI: Christine Varon and Emilie Bessède) (20 November 2020)

, Soubeyran I, Belleannée G, Evrard S, Collet D, Mégraud F, Varon C. All-trans retinoic acid targets cancer stem cells in patient’s derived primary gastric carcinoma and inhibits tumor growth. Oncogene. 2016

The word from the Director (10 April 2017)

, microenvironment interaction, cancer cell stemness and signaling pathways. Clinicians, pathologists, bacteriologists and geneticists of the University Hospital of Bordeaux are members of the teams that permits

Education: New Master "Cancer Biology" (06 May 2019)

understanding of fundamental bases and emergent areas in the field of cancer, from basic cell and molecular biology of cancer to translational and clinical research. ... Education: New Master "Cancer Biology"

New publication of Team 1 in Nature Cell Biology (21 September 2020)

Vakhrushev, Henrik Clausen, Martin J. Humphries, Frederic Saltel, Frederic A. Bard In this study, we could show that, in cancer cells, the ER-resident proteins calnexin and ERp57 are translocated to the cell ... The work of Manon Ros (PhD student) performed during the first part of her PhD in the lab of F. Bard in Singapore and in collaboration with F. Saltel, was published in Nature Cell Biology. This work ... New publication of Team 1 in Nature Cell Biology

Thesis (01 February 2021)

: November, 2020 PhD director: Christine Varon Title: Hippo signaling pathway associated to Helicobacter pylori infection in gastric cancer stem cells  ♦ Wencan HE Defense date: July, 2020 PhD director

Group V. Moreau (25 February 2022)

is a characteristic of malignant cancer cells and is one component of metastasis, the major clinical problem in cancer. Consequently, alterations in cytoskeletal signalling pathways are increasingly being recognized ... Our research focuses on the molecular bases of hepatic tumor cell invasion.

Team 3 - Oncogenesis of cutaneous lymphomas (26 November 2020)

Team leader Jean-Philippe MERLIO, PU-PH jp.merlio@u-bordeaux.fr +33 (0)5 57 57 10 27   Research description Cutaneous lymphomas are a fascinating cancer subtype with analysis at different ... Cutaneous lymphoma as a general model to study lymphoid cells oncogenesis

Group M. Bouchecareilh (25 February 2022)

glutaminolysis-mediated apoptosis in cancer cells during nutrient limitation. Nat Commun. 2017 Jan 23;8:14124. doi: 10.1038/ncomms14124. Darren M. Hutt, Daniela Martino Roth, Christelle Marchal and Marion ... Our research focuses on the identification of biomarkers and new therapeutic targets involved in liver physiopathology (Rare disease: Alpha 1-Antitrypsin Deficiency and Cancer: Hepatocellular

Teaching (29 November 2020)

program provides training that develops a broad understanding of fundamental bases and emergent areas in the field of cancer, from basic cell and molecular biology of cancer to translational and clinical